Torc2 (transducer of regulated CREB activity 2) is a key regulator of fasting glucose metabolism. Sequestered in the cytoplasm under feeding conditions,TORC2 is dephosphorylated and transported to the nucleus where it enhances CREB-dependent transcription in response to fasting stimuli.
应用类型
The antibody can be used for Western blotting (0.5–4 ug/ml).
免疫原
Synthetic peptide surrounding amino acid 676 of rat TORC2
来源宿主
兔
反应性
经检测验证,可与大鼠种属来源的TORC2蛋白发生免疫反应
保存建议
提供的100 ug TORC2抗体产品为无色溶液其浓度为0.5 mg/ml溶解于包含有30%甘油, 0.5% BSA和0.01%硫柳汞的PBS (pH 7.2)缓冲液中.请将该TORC2抗体产品置于-20 °C冷冻保存,建议分装使用以避免反复冻融.