LKB1 is a tumor suppressor that belongs to the serine/threonine kinase family. Mutation in LKB1 is link to Peutz Jeghers syndrome (PJS),a disorder characterized by the growth of polyps in the gastrointestinal tract. LKB1 regulate AMPK signaling pathway and may also play a role in chromatin remodeling,cell cycle arrest and cell polarity
应用类型
The antibody can be used for Western blotting (0.5–4 ug/ml).
免疫原
Synthetic peptide surroundign amino acid 294 of mouse LKB1
来源宿主
兔
反应性
经检测验证,可与人、小鼠、大鼠种属来源的LKB1蛋白发生免疫反应
保存建议
提供的100 ug LKB1抗体产品为无色溶液其浓度为0.5 mg/ml溶解于包含有30%甘油, 0.5% BSA和0.01%硫柳汞的PBS (pH 7.2)缓冲液中.请将该LKB1抗体产品置于-20 °C冷冻保存,建议分装使用以避免反复冻融.