C/EBP alpha helps regulate terminal adipocyte differentiation by turning on fat-specific genes required for the synthesis,uptake,and storage of long chain fatty acids. Studies have shown that C/EBP delta and C/EBP beta play an early catalytic role in the differentiation pathway,relaying the effects of the hormonal stimulants DEX and MIX in a cascade-like fashion,leading to the activation of the gene encoding C/EBP alpha.
应用类型
Western blot analysis (1-4 ug/ml). However, the optimal conditions should be determined individually. 3T3 cell lysate can be used as a positive control.
免疫原
Synthetic peptide surrounding amino acid 325 of rat C/EBP alpha.