Telomerase is an RNA-dependant DNA polymerase that catalyzes the addition of telemoric repeat，TTAGGG to chromosome ends. Telomerase is composed of an internal telomerase RNA template （TERC） and the enzyme，telomerase reverse transcriptase （TERT or TP2）. Telomerase expression is usually repressed in postnatal somatic cells resulting in shortening of telomeres. Overexpression of telomerase may be implicated with oncogenesis.
应用类型
Western blot analysis （1-4 ug/ml）. However， the optimal conditions should be determined individually. 3T3 cell lysate can be used as a positive control.
免疫原
Synthetic peptide surrounding amino acid 572 of human TP2.
来源宿主
兔
反应性
经检测验证，可与人、小鼠、大鼠种属来源的TP2蛋白发生免疫反应.
保存建议
提供的TP2抗体产品为100 ug 无色溶液，其浓度为0.5 mg/ml，溶解于包含有30%甘油， 0.5% BSA， 0.01%硫柳汞的PBS （pH 7.2）缓冲液中.请将该TP2抗体产品置于-20 ℃冷冻保存，建议分装使用以避免反复冻融.
