ALK7 or ACVR1C is a type I receptor for TGFB superfamily of signaling protein. Upon ligand binding，type I receptors phosphorylate cytoplasmic SMAD transcription factors，which then translocate to the nucleus and interact directly with DNA or in complex with other transcription factors.
应用类型
Western blot analysis （0.5-4 ug/ml）. However， the optimal conditions should be determined individually. Jurkat cell lysate and rat kidney tissue lysate can be used as positive controls.
免疫原
Synthetic peptide surrounding amino acid 155 of mouse ALK-7
来源宿主
兔
反应性
经检测验证，可与人、小鼠、大鼠种属来源的ALK-7蛋白发生免疫反应.
保存建议
提供的ALK-7抗体产品为100 ug 无色溶液，其浓度为0.5 mg/ml，溶解于包含有30%甘油， 0.5% BSA， 0.01%硫柳汞的PBS （pH 7.2）缓冲液中.请将该ALK-7抗体产品置于-20 ℃冷冻保存，建议分装使用以避免反复冻融.
