The Toll-like receptor (TLR) family of proteins are characterized by a highly conserved Toll homology (TH) domain,which is essential for Toll-induced signal transduction. TLRs require adapter molecule such as MyD88 and TIRAP to activate various kinases and transcription factors. TLR10 is homologous to TLRs 1 and 6 and is highly expressed in the lymphoid tissues.
应用类型
Western blot
免疫原
Synthetic peptide surrounding amino acid 513 of human TLR10