PINK1 （PTEN-induced putative kinase 1） is a serine/threonine protein kinase found in mitochondria. PINK1 protects cell from .stress-induced mitochondrial dysfunction. Mutation in this gene is associated with the early onset of Parkinson’s disease.
应用类型
Western blotting （0.5-4 ug/ml）. However， the optimal conditions should be determined individually. The antibody recognizes 55 kDa and 63 kDa isoforms of PINK1 in samples from human， nouse and rat origins. Reactivity to other species has not been tested.
免疫原
Synthetic peptide surrounding amino acid 488 of mouse PINK1
来源宿主
兔
反应性
经检测验证，可与人、小鼠、大鼠种属来源的PINK1蛋白发生免疫反应.
保存建议
提供的PINK1抗体产品为100 ug 无色溶液，其浓度为0.5 mg/ml，溶解于包含有30%甘油， 0.5% BSA和0.01%硫柳汞的PBS （pH 7.2）缓冲液中.请将该PINK1抗体产品置于-20 ℃冷冻保存，建议分装使用以避免反复冻融.
