EDEM1 belongs to the glycosyl hydrolase 47 family. It extracts misfolded glycoproteins，but not glycoproteins undergoing productive folding，from the calnexin cycle. It is directly involved in endoplasmic reticulum-associated degradation （ERAD） and targets misfolded glycoproteins for degradation in an N-glycan-dependent manner.
应用类型
Western blot: （1:200 dilution） Use 0.5 – 4 ug/ml based on your sample type.
免疫原
Synthetic peptide near the C-terminal of mouse EDEM1
