Xenopus Dickkopf （Dkk） was initially discovered as a Wnt antagonist that plays an important role in head formation. By far，four members of Dkk have been identified in mammals. Each Dkk molecule contains two conserved cysteine-rich domains which are separated by a 50-55 amino acid linker region. Dkk4 is a secreted glycoprotein and has three immune-reactive sites at 15-17kDa，30-32kDa and at 40kDa.
应用类型
Western blotting （0.5-4 ug/ml）. However， the optimal conditions should be determined individually. The antibody detects ~40 kDa of Dkk4 in samples from human， mouse and rat origins. Reactivity to other species has not been determined.
免疫原
Synthetic peptide surrounding amino acid 179 of mouse Dkk4
来源宿主
兔
反应性
经检测验证，可与人、小鼠、大鼠种属来源的DKK4蛋白发生免疫反应.
保存建议
提供的DKK4抗体产品为100 ug 无色溶液，其浓度为0.5 mg/ml，溶解于包含有30%甘油和0.01%硫柳汞的PBS （pH 7.2）缓冲液中.请将该DKK4抗体产品置于-20 ℃冷冻保存，建议分装使用以避免反复冻融.
