Xenopus Dickkopf (Dkk) was initially discovered as a Wnt antagonist that plays an important role in head formation. By far,four members of Dkk have been identified in mammals. Each Dkk molecule contains two conserved cysteine-rich domains which are separated by a 50-55 amino acid linker region.
应用类型
Western blotting (0.5-4 ug/ml). However, the optimal conditions should be determined individually. The antibody detects ~38 kDa of Dkk3 in samples from mouse and rat origins. Reactivity to other species has not been determined.
免疫原
Synthetic peptide surrounding amino acid 240 of rat Dkk3
来源宿主
兔
反应性
经检测验证,可与小鼠、大鼠种属来源的DKK3蛋白发生免疫反应.
保存建议
提供的DKK3抗体产品为100 ug 无色溶液,其浓度为0.5 mg/ml,溶解于包含有30%甘油和0.01%硫柳汞的PBS (pH 7.2)缓冲液中.请将该DKK3抗体产品置于-20 ℃冷冻保存,建议分装使用以避免反复冻融.