OX40 is also known as CD134 is a member of the tumor necrosis factor receptor superfamily (TNFR). OX40 plays an important role in CD4+ and CD8+T-cells and B-cells response. Binding of OX40 to its ligand,OX40L provides co-stimulatory signal to effector T-cells without CD28 activation.
应用类型
Western blotting (0.5-4 ug/ml). However, the optimal concentrations should be determined individually. The antibody recognizes the 50 kDa full length as well as the 30 kDa and 20 kDa subunits of OX40 in Western blot analysis. Reacts with rat. Other species have not been determined.
免疫原
Synthetic peptide surrounding amino acid 255 of rat OX40
来源宿主
兔
反应性
经检测验证,可与大鼠种属来源的OX40蛋白发生免疫反应.
保存建议
提供的OX40抗体产品为100 ug 无色溶液,其浓度为0.5 mg/ml,溶解于包含有30%甘油, 0.5% BSA和0.01%硫柳汞的PBS缓冲液中.请将该OX40抗体产品置于-20 ℃冷冻保存,建议分装使用以避免反复冻融.