Sox genes encode for transcriptional regulators that are involved in the early embryonic develpoment and in the determination of cell fate. Sox2 is also known as SRY （sex determining region Y）-box2，contain genes that encode for the HMG-box domain that is responsible for DNA binding activity. Mutation of Sox2 genes is link to optic nerve hypoplasia and anophthalmia，a severe form of eye deformity.
应用类型
Western blotting （0.5-1 ug/ml）. However， the optimal conditions should be determined individually. Other applications have not been tested. The antibody detects ~35kDa of Sox2 in samples from mouse origins.
免疫原
Synthetic peptide surrounding amino acid 301 of human Sox2
来源宿主
兔
反应性
经检测验证，可与人、小鼠、大鼠、猪、牛、狗、绵羊种属来源的Sox-2蛋白发生免疫反应.
保存建议
提供的Sox-2抗体产品为100 ug 无色溶液，其浓度为0.5 mg/ml，溶解于包含有30%甘油和0.01%硫柳汞的PBS （pH 7.2）缓冲液中.请将该Sox-2抗体产品置于-20 ℃冷冻保存，建议分装使用以避免反复冻融.
