Relaxin is a peptide hormone belonging to the insulin gene superfamily. It is made by the corpora lutea of the ovaries during pregnancy in many mammalian species. The secretion of the hormone into the blood stream just before parturition results in softening and lengthening of the pubic symphysis and a softening of the cervix,which facilitates the process of birth. nRelaxin-1 is proteolytically processed into a hetorodimer that has two peptide chains,A and B that are covalently linked by disulfide bonds.
应用类型
Western blotting (0.5-4 ug/ml). However, the optimal concentrations should be determined individually. Other applications have not been tested. The antibody recognizes Relaxin-1 (~20 kDa) and its dimer form (~40 kDa) in samples from human, mouse and rat origins. Other species have not been tested.
免疫原
Synthetic peptide corresponding to residues surrounding amino acid 130 of rat Relaxin-1
来源宿主
兔
反应性
经检测验证,可与人、小鼠、大鼠种属来源的Relaxin 1蛋白发生免疫反应.
保存建议
提供的Relaxin 1抗体产品为100 ug 无色溶液,其浓度为0.5 mg/ml,溶解于包含有30%甘油, 0.5% BSA和0.01%硫柳汞的PBS缓冲液中.请将该Relaxin 1抗体产品置于-20 ℃冷冻保存,建议分装使用以避免反复冻融.