Matriptase or MT-SP1 is an epithelial-derived type II transmembrane serine protease that is highly expressd in human cancer-derived cell lines. Matriptase cleaves and activates protease activated receptor-2，pro-urokinase plasminogen activator and pro-hepatocyte growth factor. Matriptase is strongly inhibited by the hepatocyte growth factor activator inhibitor type 1 (HAI-1)，which is a reactive site loop of Kunitz domain and also a transmembrane serine protease inhibitor.
应用类型
Western blot
免疫原
Synthetic peptide surrounding amino acid 629 of rat Matriptase
