Matriptase or MT-SP1 is an epithelial-derived type II transmembrane serine protease that is highly expressd in human cancer-derived cell lines. Matriptase cleaves and activates protease activated receptor-2，pro-urokinase plasminogen activator and pro-hepatocyte growth factor. Matriptase is strongly inhibited by the hepatocyte growth factor activator inhibitor type 1 （HAI-1），which is a reactive site loop of Kunitz domain and also a transmembrane serine protease inhibitor.
应用类型
Western blotting （0.5-4 ug/ml）. However， the optimal concentrations should be determined individually. The antibody recognizes ~75 kDa doublets of Matriptase in samples from human， mouse and rat， origins. Reactivity to other species has not been tested.
免疫原
Synthetic peptide surrounding amino acid 629 of rat Matriptase
来源宿主
兔
反应性
经检测验证，可与人、小鼠、大鼠种属来源的Matriptase蛋白发生免疫反应.
保存建议
提供的Matriptase抗体产品为100 ug 无色溶液，其浓度为0.5 mg/ml，溶解于包含有30%甘油， 0.5% BSA和0.01%硫柳汞的PBS缓冲液中.请将该Matriptase抗体产品置于-20 ℃冷冻保存，建议分装使用以避免反复冻融.
