- 中文名称
Glucose Regulated Protein 78 (GRP78) BioAssay ELISA Kit (Rat)
- 英文名字
- Glucose Regulated Protein 78 (GRP78) BioAssay ELISA Kit (Rat)
- 供应商
- USBiological
- 产品货号
- 385074
- 产品报价
- ￥1/96Tests
- 产品说明书
- 点击查看
- 购买方式
- 银行转账、电汇、支票、现金，在线支付宝及网银支付，或直接与我们电话联系400-6800-868
- 产品新闻
- 背景资料
- USBiological品牌是全球有名的抗原抗体和生化试剂供应商，生产世界上种类最多的抗体，用于Western Blot、免疫沉淀、免疫荧光、免疫组化和流式细胞术等多种检测方法。武汉艾美捷科技作为USBiological品牌中国区域总代理，是行业中少有的致力于服务客户，帮助客户，且拥有独立的专业销售团队、技术支持团队、市场营销团队、进出口报关团队的高科技生物企业。可以为您提供及时的咨询响应，专业的产品和解决方案支持，稳健快捷的交货周期，优质放心的售后服务。我们致力于为您提供有价值的产品和服务，在意您的成功！
- 产品描述
- GRP78 is a ubiquitously expressed, 78kD glucose-regulated protein, and is commonly referred to as an immunoglobin chain binding protein (BiP). The BiP proteins are categorized as stress response proteins because they play an important role in the proper folding and assembly of nascent protein and in the scavenging of misfolded proteins in the endoplasmic reticulum lumen. Translation of BiP is directed by an internal ribosomal entry site (IRES) in the 5’ nontranslated region of the BiP mRNA. BiP IRES activity increases when cells are heat stressed (1). GRP78 is also critical for maintenance of cell homeostasis and the prevention of apoptosis (2). Luo et al. have provided findings that suggest GRP78 is essential for embryonic cell growth and pluripotent cell survival (3). In terms of diseases, GRP78 has been shown to be a reliable biomarker of hypoglycemia, to serve a neuroprotective function in neurons exposed to glutamate and oxidative stress (4), and its protein levels are reduced in the brains of Alzheimer’s patients (5). Also, the induction of the GRP78 protein that results in severe glucose and oxygen deprivation could possible lead to drug resistance to antitumor drugs (6, 7).Sample Type:TissueIntended Use:This ELISA BioAssay kit is used to quantitate GRP78 concentration in rat samples.Sensitivity:0.15ng/mlRange:0-50ng/mlSpecificity:Recognizes rat GRP78.Test Principle:This ELISA BioAssay Kit (Rat) is a sandwich ELISA that can be used for the quantification of Rat GRP78 in Tissue Lysates. The ELISA utilizes an Anti-Rat GRP78 monoclonal antibody-coated plate and a Biotinylated antibody for detection which allows for an assay range of 0-50ng/mL, with a sensitivity of 0.15ng/mL. The other highlights of this BioAssay kit are a quick incubation time, stable reagents, and an easy to use protocol.Kit Components:ELISA Plate, 1x96wellsStandard, 2x56.7ngStandard and Sample Diluent, 1x50mLBiotinylated Antibody Concentrate, 1x150uL10X Wash Buffer Concentrate, 1x100mLBiotinylated Antibody Diluent, 1x13mLStreptavidin Poly HRP Concentrate, 1x150uLStreptavidin Poly HRP Diluent, 1x13mLTMB Substrate, 1x13mLStop Solution, 1x13mLStorage and Stability:Store powder at 4°C liquid at -20°C. Store other components at 4°C. Stable for at least 6 months For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
- 产品特点
- 针对Glucose Regulated Protein 78 (GRP78) BioAssay ELISA Kit (Rat)该产品的特点优势，欢迎查阅官网提供的产品说明书。
- 保存建议
- 建议收到Glucose Regulated Protein 78 (GRP78) BioAssay ELISA Kit (Rat)产品后将其置于4°C保存。
- 其他
- Usbiological公司是美国著名的抗体和生化试剂供应商，生产世界上种类最多的抗体，用于Western Blot、免疫沉淀、免疫荧光、免疫组化和流式细胞术等多种检测方法。Usbiological公司现已拥有超过50,19234种抗体、抗原和生化产品，为科研用户提供了诸多超值选择。
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- 注意
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该页面的中文产品信息的翻译，仅供参考。准确的产品信息请以厂家的英文说明书为准。下单前，请浏览说明书确认。
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