Breast tumor kinase，Brk （also known as PTK6），is a member of intracellular tyrosine kinase family that is thought to be related to Src family of tumor related kinases. Brk is expressed in breast carcinomas but not in normal breast tissue. The presence of Brk in the nucleus appears to be linked to suppression of tumor progression and has been shown to undergo autophosphorylation.
应用类型
Western blotting （0.5-4 ug/ml）. However， the optimal conditions should be determined individually. The antibody recognizes ~57 kDa Brk of human， mouse， and rat origins. Reactivity to other species has not been tested.
免疫原
Synthetic peptide corresponding to residues surrounding amino acids 508 of human Brk
来源宿主
兔
反应性
经检测验证，可与人、小鼠、大鼠种属来源的Brk蛋白发生免疫反应.
保存建议
提供的Brk抗体产品为100 ug 无色溶液，其浓度为0.5 mg/ml，溶解于包含有30%甘油， 0.5% BSA， 0.01%硫柳汞的PBS （pH 7.2）缓冲液中.请将该Brk抗体产品置于-20 ℃冷冻保存，建议分装使用以避免反复冻融.
