DMP-1 (Dentin matrix protein1) is a member of the integrin ligand N-linked glycoprotein family.It is mostly found in bone,tooth and hypertrophic cartilage. DMP-1 plays an important role in dentin and bone mineralization. DMP-1 has multiple serine,glutamic acid and aspartic acid residues,a GAG attachement site and RGD motif. DMP-1 is proteolytically proceesed into mulitple fragemtns in the extracellular matrix (ECM) of bone and dentin.
应用类型
Western blotting (0.5-4 ug/ml). However, the optimal conditions should be determined individually. The antibody recognizes ~60-130 kDa DMP- 1 of human, mouse, and rat origins. Reactivity to other species has not been tested.
免疫原
Synthetic peptide corresponding to residues surrounding amino acids 21 of rat DMP-1
来源宿主
兔
反应性
经检测验证,可与人、小鼠、大鼠种属来源的DMP1蛋白发生免疫反应.
保存建议
提供的DMP1抗体产品为100 ug 无色溶液,其浓度为0.5 mg/ml,溶解于包含有30%甘油, 0.5% BSA, 0.01%硫柳汞的PBS (pH 7.2)缓冲液中.请将该DMP1抗体产品置于-20 ℃冷冻保存,建议分装使用以避免反复冻融.