Non-T cell Activation Linker (NTAL) is also known as linker for activation of B cells (LAB)，is a transmembrane adaptor protein. NTAL is expressed in B cells，mast cells，monocytes and NK cells. When NTAL is tyrosine phosphorylated，it recruits signalling molecules such as Grb2，Gab2 and c-Cbl into receptor-signalling complexes. Mutation in the NTAL gene may cause Williams-Beuren syndrome，a rare genetic disorder.
应用类型
Western blot
免疫原
Synthetic peptide surrounding amino acid 187 of rat NTAL
