Myeloperoxidase (MPO) is highly expressed in neutrophils and polymorphonuclear luekocytes. MPO is expressed as a dimer in regular neutrophils with a 140kDA. The glycoslated form of MPO has a molecular weight of 92kDa and when undergoes a final glycoslyation,MPO forms subunits of 60kDa and 12kDa. In recent studies,MPO was shown to be involved in the initiation and progression of cardiovascular disease.
应用类型
Western blot
免疫原
Synthetic peptide surrounding amino acid 765 of human MPO