Myeloperoxidase (MPO) is highly expressed in neutrophils and polymorphonuclear luekocytes. MPO is expressed as a dimer in regular neutrophils with a 140kDA. The glycoslated form of MPO has a molecular weight of 92kDa and when undergoes a final glycoslyation,MPO forms subunits of 60kDa and 12kDa. In recent studies,MPO was shown to be involved in the initiation and progression of cardiovascular disease.
应用类型
Western blotting (0.5-4 ug/ml). However, the optimal concentrations should be determined individually. The antibody recognizes 60-100 kDa MPO from samples of human, mouse, and rat origins. Reactivity to other species has not been tested.
免疫原
Synthetic peptide surrounding amino acid 765 of human MPO
来源宿主
兔
反应性
经检测验证,可与人、小鼠种属来源的Myeloperoxidase (MPO)蛋白发生免疫反应.
保存建议
提供的Myeloperoxidase (MPO)抗体产品为100 ug 无色溶液,其浓度为0.5 mg/ml,溶解于包含有30%甘油, 0.5% BSA和0.01%硫柳汞的PBS缓冲液中.请将该Myeloperoxidase (MPO)抗体产品置于-20 ℃冷冻保存,建议分装使用以避免反复冻融.