Nectin is a cell-adhesion molecule that belongs to the immunoglobilin superfamily and is also known as the poliovirus receptor-related protein or PPR. Nectin family consists of Nectin 1 which expressed abundantly in the brain and Nectin 2 and 3 which are ubiquitously expressed in cells where cadherin are not expressed. Nectin-3 or PPR3 is a transmembrane protein that has three splicing variants: Nectin3,Nectin 3B and Nectin 3g. Nectin-3 is mainly expressed in the testis and placental tissues and interacts in vivo with both long and short isoforms of afadin.
应用类型
Western blot
免疫原
Synthetic peptide corresponding to residues surrounding amino acids 536 of mouse Nectin-3