Nectin is a cell-adhesion molecule that belongs to the immunoglobilin superfamily and is also known as the poliovirus receptor-related protein or PPR. Nectin family consists of Nectin 1 which expressed abundantly in the brain and Nectin 2 and 3 which are ubiquitously expressed in cells where cadherin are not expressed. Nectin-3 or PPR3 is a transmembrane protein that has three splicing variants: Nectin3，Nectin 3B and Nectin 3g. Nectin-3 is mainly expressed in the testis and placental tissues and interacts in vivo with both long and short isoforms of afadin.
应用类型
Western blotting （0.5-4 ug/ml）. However， the optimal conditions should be determined individually. The antibody recognizes ~ 83 kDa Nectin-3 of mouse and rat origins. Reactivity to other species has not been tested.
免疫原
Synthetic peptide corresponding to residues surrounding amino acids 536 of mouse Nectin-3
来源宿主
兔
反应性
经检测验证，可与小鼠、大鼠种属来源的Nectin-3/CD113蛋白发生免疫反应.
保存建议
提供的Nectin-3/CD113抗体产品为100 ug 无色溶液，其浓度为0.5 mg/ml，溶解于包含有30%甘油， 0.5% BSA， 0.01%硫柳汞的PBS （pH 7.2）缓冲液中.请将该Nectin-3/CD113抗体产品置于-20 ℃冷冻保存，建议分装使用以避免反复冻融.
