Yes-associated protein (YAP) was identified based on its ability to associate with the SH3 domain of Yes. It also binds to other SH3 domain containing proteins such as Nck,Crk,Src,and Abl. YAP is a transcriptional coactivator. It interacts with 13-3-3 and suppresses apoptosis.
应用类型
Western blot
免疫原
Synthetic peptide surrounding amino acid 279 of human YAP1