Yes-associated protein (YAP) was identified based on its ability to associate with the SH3 domain of Yes. It also binds to other SH3 domain containing proteins such as Nck,Crk,Src,and Abl. YAP is a transcriptional coactivator. It interacts with 13-3-3 and suppresses apoptosis.
应用类型
Western blotting (0.5-4 ug/ml). Jurkat cell lysate can be used as a positive control. Other applications have not been tested.
免疫原
Synthetic peptide surrounding amino acid 279 of human YAP1
来源宿主
兔
反应性
经检测验证,可与人种属来源的YAP1蛋白发生免疫反应.
保存建议
提供的YAP1抗体产品为100 ug 无色溶液,其浓度为0.5 mg/ml,溶解于包含有30%甘油, 0.5% BSA和0.01%硫柳汞的PBS缓冲液中.请将该YAP1抗体产品置于-20 ℃冷冻保存,建议分装使用以避免反复冻融.