Triglycerides form an important energy store in many living organisms. Adipose tissue serves as the primary storage depot for triglycerides in mammals. Lipolytic enzymes mobilize triglycerides during periods of starvation to provide organisms with necessary energy. Hormone-sensitive lipase （HSL），the first identified lipolytic enzyme，hydrolyzes triglycerides in mammalian adipose tissues. Additional lipolytic enzymes，including adipose triglyceride lipase （ATGL），have also been discovered. The primary function of ATGL is to catalyze the hydrolysis of the first ester bond of lipid molecules. This enzyme may provide diglyceride substrates for HSL hydrolysis. ATGL is abundantly expressed in murine white and brown adipose tissue，and is highly substrate specific. ATGL was independently identified as desnutrin and the TG-hydrolace inducible phospholipase-A2-z.
应用类型
Western blotting （0.5-4 ug/ml） and immunoprecipitation. recognizes 54 kDa ATGL in samples from human， mouse and rat origins. However， the optimal concentrations should be determined individually.
免疫原
Synthetic peptide corresponding to residues surrounding amino acids 385 of human ATGL
来源宿主
兔
反应性
经检测验证，可与人、小鼠、大鼠种属来源的ATGLAntibody发生免疫反应.
保存建议
提供的ATGLAntibody产品为100 ug 无色溶液，其浓度为0.5 mg/ml，溶解于包含有30%甘油， 0.5% BSA和0.01%硫柳汞的PBS缓冲液中.请将该ATGLAntibody产品置于-20 ℃冷冻保存，建议分装使用以避免反复冻融.
