The cysteine proteases termed lysosomal cathepsins have long been thought to be primarily involved in end-stage protein breakdown within lysosomal compartments. Cathepsin L functions to regulate cell cycle progression through proteolytic processing of the CDP/Cux transcription factor.
应用类型
Western blotting （0.5-4 ug/ml）. However， the optimal concentrations should be determined individually. The antibody recognizes the mature form of Cathepsin L （25 kDa） from human， mouse and rat origins. Reactivity to other species has not been tested. Rat kidney tissue lysate can be used as a positive control.
免疫原
Synthetic peptide surrounding amino acid 223 of rat Cathepsin L
来源宿主
兔
反应性
经检测验证，可与人、小鼠、大鼠种属来源的Cathepsin L （Cleaved）蛋白发生免疫反应.
保存建议
提供的Cathepsin L （Cleaved）抗体产品为100 ug 无色溶液，其浓度为0.5 mg/ml，溶解于包含有30%甘油， 1% BSA和0.02%硫柳汞的PBS缓冲液中.请将该Cathepsin L （Cleaved）抗体产品置于-20 ℃冷冻保存，建议分装使用以避免反复冻融.
