Calsenilin is also known as DREAM and KChlP3. Calsenilin interacts with presenilin-2,a protein involved in Alzheimer’s disease,to reverse presenilin mediated enhancement of calcium signaling. Calsenilin also has pro-apoptotic function,is a substrate for caspase-3,acts as a calcium regulated transcriptional suppressor,and interacts with A-type potassium channels.
应用类型
Western blot
免疫原
Synthetic peptide surrounding amino acid 107 of human Calsenilin