Senescence is thought to be a tumor suppressive mechanism and an underlying cause of aging. Senescence represents an arrested state in which the cells remain viable，but not stimulated to divide by serum or passage in culture. Senescent cells display increase of cell size，senescence-associated expression of beta-galactosidase （SA-beta-Gal） activity，and altered patterns of gene expression.Intended Use：Detection of senescence in cellsScreening potential senescence inducers/inhibitorsSample Type：Adherent and suspension cellsSpecificity：MammalianTest Principle：The Senescence detection BioAssay kit is designed to fluorescently detect SA-beta-Gal activity in cultured cells by FACS. The SA-beta-Gal is present only in senescent cells and is not found in pre-senescent，quiescent or immortal cells.Kit Components：Wash Buffer. 1x100mlSenescence Dye，1x150ulStorage and Stability：Store powder at 4°C liquid at -20°C. Store other components at 4°C. Stable for at least 6 months For maximum recovery of product，centrifuge the original vial after thawing and prior to removing the cap.
