Senescence is thought to be a tumor suppressive mechanism and an underlying cause of aging. Senescence represents an arrested state in which the cells remain viable，but not stimulated to divide by serum or passage in culture. Senescent cells display increase of cell size，senescence-associated expression of beta-galactosidase （SA-beta-Gal） activity，and altered patterns of gene expression.Intended Use：The Senescence Detection BioAssay Kit is designed to histochemically detect specific senescence marker in distinct pH in cultured cells and tissue sections.Specificity：MammalianTest Principle：The Senescence detection BioAssay kit is designed to histochemically detect SA-beta-Gal activity in cultured cells and tissue sections，a known characteristic of senescent cells. The SA-beta-Gal is present only in senescent cells and is not found in presenescent，quiescent or immortal cells.Kit Components：Fixative Solution （1X），1x125mlX-Gal （150mg，lyophilized），1x1vialStaining Solution （1X），1x125mlStaining Supplement （100X），1x1.5mlStorage and Stability：Store powder at 4°C liquid at -20°C. Store other components at 4°C. Stable for at least 6 months For maximum recovery of product，centrifuge the original vial after thawing and prior to removing the cap.
