Histone acetyltransferases (HATs) have been implicated in a number of cellular functions including gene regulation,DNA synthesis,and repair. Histone acetyltransferases and deacetylases are,respectively,the enzymes devoted to the addition and removal of acetyl groups from lysine residues on the histone N-terminal tails. The enzymes exert fundamental roles in developmental processes and their deregulation has been linked to the progression of diverse human disorders,including cancer.
应用类型
Western blot
免疫原
Synthetic peptide surrounding amino acid 445 of human HAT-1