Histone acetyltransferases （HATs） have been implicated in a number of cellular functions including gene regulation，DNA synthesis，and repair. Histone acetyltransferases and deacetylases are，respectively，the enzymes devoted to the addition and removal of acetyl groups from lysine residues on the histone N-terminal tails. The enzymes exert fundamental roles in developmental processes and their deregulation has been linked to the progression of diverse human disorders，including cancer.
应用类型
Western blotting （1-2 ug/ml）. However， the optimal concentrations should be determined individually. The antibody recognizes 50 kDa HAT-1 from samples of human， mouse and rat origins. Jurkat cell lysate （Cat.# 2401-100） can be used as a positive control.
免疫原
Synthetic peptide surrounding amino acid 445 of human HAT-1
来源宿主
兔
反应性
经检测验证，可与人、小鼠、大鼠种属来源的HAT-1 蛋白发生免疫反应.
保存建议
提供的HAT-1 抗体产品为100 ug 无色溶液，其浓度为0.2 mg/ml，溶解于包含有30%甘油， 0.5% BSA和0.01%硫柳汞的PBS缓冲液中.请将该HAT-1 抗体产品置于-20 ℃冷冻保存，建议分装使用以避免反复冻融.
