The p21-activated kinase (PAK) family of serine/threonine kinases is engaged in multiple cellular processes,including cytoskeletal recognization,MAPK signaling,apoptotic signaling,control of phagocytes,NADPH oxidase and growth factor-induced neurite outgrowth. Research indicates that phosphorylation of serine 139 of PAK3 which is located in the kinase inhibitory domain,affects the kinase activity.
应用类型
Western blot
免疫原
Synthetic peptide surrounding amino acid 548 of human PAK3