TAB1 （TAK1 binding protein 1） is an adaptor protein that can activate TAK1 in vivo through phosphorylation of TAK1，a mitogen-activated protein kinase kinase kinase. Once activated TAK1 phosphorylates MAPK kinase MKK4 and MKK3/6，which activate p38 MAPK and JNK，respectively.
应用类型
Western blotting （1-4 ug/ml）. The optimal concentrations should be determined individually. The antibody recognizes TAB1 in samples from human， mouse and rat origins. BaF3 cells can be used as positive controls. A ~60 kDa band should be detected.
免疫原
Synthetic peptide mapping to the C-terminus of human TAB1
来源宿主
兔
反应性
经检测验证，可与人、小鼠、大鼠种属来源的TAB1蛋白发生免疫反应.
保存建议
提供的TAB1抗体产品为100 ug 无色溶液，其浓度为0.5 mg/ml，溶解于包含有50%甘油， 1% BSA和0.02%硫柳汞的PBS缓冲液中.请将该TAB1抗体产品置于-20 ℃冷冻保存，建议分装使用以避免反复冻融.
