Bcl-rambo shares the common structural characteristics with other members of the anti-apoptotic Bcl-2 family members,but differs from them at its C-terminus,where a 250 amino acid sequence proceeds the membrance anchor region. It also differs from other pro-apoptotic Bcl-2 family members in that it membrane anchor C-terminus region is responsible for its apoptotic activity,not its Bcl-2 homology motifs.
应用类型
Western blot
免疫原
Synthetic peptide corresponding to residues surrounding amino acids 421 of Mouse Bcl-rambo