Bcl-rambo shares the common structural characteristics with other members of the anti-apoptotic Bcl-2 family members,but differs from them at its C-terminus,where a 250 amino acid sequence proceeds the membrance anchor region. It also differs from other pro-apoptotic Bcl-2 family members in that it membrane anchor C-terminus region is responsible for its apoptotic activity,not its Bcl-2 homology motifs.
应用类型
Western blotting (0.5-4 ug/ml). However, the optimal concentrations should be determined individually. The antibody recognizes ~56 kDa band in samples from human, mouse and rat origins. Reactivity to other species has not been tested.
免疫原
Synthetic peptide corresponding to residues surrounding amino acids 421 of Mouse Bcl-rambo
来源宿主
兔
反应性
经检测验证,可与人、小鼠、大鼠种属来源的Bcl-Rambo蛋白发生免疫反应.
保存建议
提供的Bcl-Rambo抗体产品为100 ug 无色溶液,其浓度为0.2 mg/ml,溶解于包含有0.1% BSA, 30%甘油和0.01%硫柳汞的PBS缓冲液中.请将该Bcl-Rambo抗体产品置于-20 ℃冷冻保存,建议分装使用以避免反复冻融.