Tumor Endothelial Markers （TEMs，TEM 1-9） are recently identified genes，whose expression is elevated in tumor-associated endothelium. TEMs are barely detectable in normal endothelial cells. TEM8 has been shown to interact with C5 domain of collagen a3（VI），a protein also preferentially expressed in tumor endothelium. It is thought that TEM8 may play a role in tumor angiogenesis.
应用类型
Western blotting （0.5-4 ug/ml）. However， the optimal concentrations should be determined individually. The antibody recognizes ~80-85 kDa doublet of TME8 in samples from human， mouse and rat origins. Reactivity to other species has not been tested.
免疫原
Synthetic peptide corresponding to residues surrounding amino acids 484 of Mouse TEM8
来源宿主
兔
反应性
经检测验证，可与人、小鼠、大鼠种属来源的TEM-8/ATR1蛋白发生免疫反应.
保存建议
提供的TEM-8/ATR1抗体产品为100 ug 无色溶液，其浓度为0.2 mg/ml，溶解于包含有0.5% BSA， 30%甘油和0.01%硫柳汞的PBS缓冲液中.请将该TEM-8/ATR1抗体产品置于-20 ℃冷冻保存，建议分装使用以避免反复冻融.
