Endothelial lipase (EL) is a member of the triglyceride lipase gene family. It functions primarily as a phospholipase and has low triglyceride lipase activity. It was originally cloned from endothelial cells and found to be expressed in high level in the liver,placenta,lung,ovary,and macrophage. The wide spread distribution of this protein suggests it plays a general role in lipid metabolism. Human endothelial lipase has an estimated molecular weight of 57 kDa.
应用类型
Western blotting (0.5-4 ug/ml), Immunohistochemistry (5-20 ug/ml, frozen & paraffin sections, human thyroid). However, the optimal conditions should be determined individually. The antibody detects 57 kDa band in samples from human, mouse, rat, porcine, and ovine origins.
免疫原
Synthetic peptide surrounding amino acid 22 of human Endothelial Lipase