Decorin is a member of the small，leucine-rich proteoglycan （SLRP） family along with biglycan. Found in the interterritorial region of cartilage，decorin interacts with collagen and other matrix proteins to regulate the cartilaginous matrix. It has been shown to interact with fibronectin，thrombospondin，C1q，epidermal growth factor receptor （EGFR），and TGF-B. It is believed that decorin also plays a role in the cell cycle of chondrocytes.
应用类型
Western blotting （0.5-4 ug/ml）. However， the optimal conditions should be determined individually. Other applications have not been determined. The antibody detects ~22 kDa protein representing the Decorin fragment generated by digestion of human Decorin by MMP-3.
免疫原
Synthetic peptide surrounding amino acid 130 of human Decorin
来源宿主
兔
反应性
经检测验证，可与人、小鼠、大鼠、兔、猪种属来源的Decorin蛋白发生免疫反应.
保存建议
提供的Decorin抗体产品为100 ug 无色溶液，其浓度为0.5 mg/ml，溶解于包含有25%甘油， 0.5% BSA和0.01%硫柳汞的PBS （pH 7.2）缓冲液中.请将该Decorin抗体产品置于-20 ℃冷冻保存，建议分装使用以避免反复冻融.
