ROBO4 contains two fibronectin type-III domains and two Ig-like C2-type domains. ROBO4 is predominantly expressed in vascular endothelium and is considered important for vascular development. ROBO4 is a receptor for Slit proteins and may mediate the inhibition of primary endothelial cell migration by Slit proteins.
应用类型
Western blotting (1-4 ug/ml). However, the optimal conditions should be determined individually. The antibody detects the ROBO4 band in human samples.
免疫原
Synthetic peptide surrounding amino acid 322 of rat ROBO4