HDAC family are divided into two classes，I and II. Class I of the HDAC family comprises four members，HDAC-1，2，3，and 8. Class II of the HDAC family comprises HDAC-4，5，6，and 7，the molecular weights of which are all about two-fold larger than those of the class I members. Human HDAC-1，2 and 3 were expressed in various tissues，but the others （HDAC-4，5，6，and 7） showed tissue-specific expression patterns. These results suggest that each member of the HDAC family exhibits a different，individual substrate specificity and function in vivo.
应用类型
Western blotting （0.5-4 ug/ml）， However， the optimal concentrations should be determined individually. The antibody recognizes 74 kDa HDAC-10 of human， mouse， and rat origins. A 55 kDa cleavage fragment can also be detected in mouse and rat tissue lysates.
免疫原
Synthetic peptide near the N-terminus of human HDAC-10
来源宿主
兔
反应性
经检测验证，可与人、小鼠、大鼠种属来源的HDAC10蛋白发生免疫反应.
保存建议
提供的HDAC10抗体产品为100 ug 无色溶液，其浓度为0.2 mg/ml，溶解于包含有30%甘油， 0.5% BSA和0.01%硫柳汞的PBS缓冲液中.请将该HDAC10抗体产品置于-20 ℃冷冻保存，建议分装使用以避免反复冻融.
