Apoptosis plays an important role in many cellular processes. Dio-1 (Death Inducer-O bliterator-1)，a putative transcription factor，has been indicated to function in the onset of apoptosis. Dio-1 expression is upregulated when an apoptosis is detected. It translocates to the nucleus，and activates apoptosis during limb development. Dio-1 expression can be suppressed by caspase inhibitors and Bcl-2 expression.
应用类型
Western blot
免疫原
Synthetic peptide near the N-terminus of mouse Dio-1
