TROY (also designated TAJ),a member of the TNFR superfamily,exists as several isoforms that vary in functions. Full length TROY contains a cytoplasmic tail,which recruits tumor necrosis factor receptor-associated factor (TRAF) 2. The interaction between TROY and TRAF2 promotes cell survival through the NFκB signaling pathway. One truncated version of TROY,designated TNFRSF19,contains a shortened cytoplasmic tail,which prevents TNFRSF19 from activating the NFκB signal transduction pathway.
应用类型
Western blotting (1-4 ug/ml). However, the optimal concentrations should be determined individually. The antibody recognizes mouse TROY. Reactivity to other species has not been tested.
免疫原
Synthetic peptide mapping to the C-terminus of mouse TROY
来源宿主
兔
反应性
经检测验证,可与小鼠种属来源的TROY/TAJ蛋白 发生免疫反应.
保存建议
提供的TROY/TAJ抗体 产品为100 ug 无色溶液,其浓度为0.5 mg/ml,溶解于包含有30%甘油, 0.5% BSA和0.01%硫柳汞的PBS缓冲液中.请将该TROY/TAJ抗体 产品置于-20 ℃冷冻保存,建议分装使用以避免反复冻融.