The Toll-like receptor (TLR) family of proteins are characterized by a highly conserved Toll homology (TH) domain,which is essential for Toll-induced signal transduction. TLR9 has been suggested as a receptor for unmethylated CpG dinucleotides in the bacterial DNA. TLR9 is highly expressed in the spleen.
应用类型
Western blotting (0.5-4 ug/ml). However, the optimal conditions should be determined individually. The antibody recognizes ~113 kDa of full length and the 65 kDa cleaved fragment in Jurkat cell lysate. Reactivity to other species has not been tested.
免疫原
Synthetic peptide surrounding amino acid 931 of mouse TLR9
来源宿主
兔
反应性
经检测验证,可与人、小鼠、大鼠、猪种属来源的TLR9蛋白发生免疫反应.
保存建议
提供的TLR9抗体产品为100 ug 无色溶液,其浓度为0.5 mg/ml,溶解于包含有30%甘油, 0.5% BSA和0.01%硫柳汞nn的PBS (pH 7.2)缓冲液中.请将该TLR9抗体产品置于-20 ℃冷冻保存,建议分装使用以避免反复冻融.