Proteins of the matrix metalloprotease (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes,such as embryonic development,reproduction,and tissue remodeling as well as disease processes such as arthritis and metastasis. Most MMP’s are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases.
应用类型
Western blot
免疫原
Synthetic peptide surrounding amino acid 465 of rat MMP-3