Proteins of the matrix metalloprotease （MMP） family are involved in the breakdown of extracellular matrix in normal physiological processes，such as embryonic development，reproduction，and tissue remodeling as well as disease processes such as arthritis and metastasis. Most MMP’s are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases.
应用类型
Western blotting （0.5-4 ug/ml）. However， the optimal concentrations should be determined individually. The antibody recognizes the MMP-3 of human， mouse， rat， horse， and rabbit origins. Reactivity to other species has not been tested. The antibody detects the 55 kDa full length and the 21 kDa cleavage fragment of MMP-3.
免疫原
Synthetic peptide surrounding amino acid 465 of rat MMP-3
来源宿主
兔
反应性
经检测验证，可与人、小鼠、大鼠、马、兔种属来源的MMP-3蛋白 发生免疫反应.
保存建议
提供的MMP-3抗体 产品为100 ug 无色溶液，其浓度为0.5 mg/ml，溶解于包含有30%甘油， 0.5% BSA和0.01%硫柳汞的PBS缓冲液中.请将该MMP-3抗体 产品置于-20 ℃冷冻保存，建议分装使用以避免反复冻融.
