The matrix metalloproteinases (MMP) are a family of peptidase enzymes responsible for the degradation of extracellular matrix components,including collagen,gelatin,fibronectin,laminin and proteoglycan. Transcription of MMP genes is differentially activated by phorbol ester,lipopolysaccharide (LPS) or staphylococcal enterotoxin B (SEB). MMP catalysis requires both calcium and zinc. MMP-3,MMP-10,and MMP-11 activates procollagenase.
应用类型
Western blotting (1-4 ug/ml), immunoprecipitation (10-20 ug/ml), and Immunohistochemistry (15-25 ug/ml). However, the optimal concentrations should be determined individually. The antibody recognizes MMP3 of human, mouse, and rat origins.
免疫原
Recombinant human MMP3
来源宿主
山羊
反应性
经检测验证,可与人、小鼠、大鼠种属来源的MMP-3蛋白 发生免疫反应.
保存建议
提供的MMP-3抗体 产品为100 ug 无色溶液,其浓度为0.5 mg/ml,溶解于包含有50%甘油, 1% BSA和0.02% 叠氮钠的PBS缓冲液中.请将该MMP-3抗体 产品置于-20 ℃冷冻保存,建议分装使用以避免反复冻融.