BRD8 interacts with thyroid hormone receptor in a ligand-dependent manner and enhances thyroid hormone-dependent activation from thyroid response elements. BRD8 contains a bromodomain and is thought to be a nuclear receptor coactivator. Three alternatively spliced BRD8 transcript variants that encode distinct BRD8 isoforms have been identified.
应用类型
Western blotting （1-4 ug/ml）. However， the optimal conditions should be determined individually. The antibody detects BRD8 in Human， mouse and rat samples.
免疫原
Synthetic peptide surrounding amino acid 1000 of rat BRD8
