Human HtrA2 （also designated Omi） is a novel member of the HtrA serine protease family and is highly homologous to HtrA （also known as L56 and HtrA1）. HtrA2 is ubiquitously expressed nuclear protease that is capable of autoproteolysis. The HtrA2 protein exists as two polypeptides of 38 and 40 kDa and as an alternatively spliced form called D-Omi，which is predominately expressed in the kidney，colon and thyroid. Like HtrA，HtrA2 is involved in the degradation aberrantly folded proteins during conditions of cellular stress，suggesting that it may possess a chaperone-like role under normal conditions.
应用类型
Western blotting （1-2 ug/ml） and immunofluorescence （20 ug/ml）. However， the optimal concentrations should be determined individually. The antibody recognizes the full length and the mitochondria-processed HtrA2/Omi.
免疫原
Recombinant human HtrA2/Omi
来源宿主
兔
反应性
经检测验证，可与人、小鼠、大鼠种属来源的HtrA2/Omi蛋白 发生免疫反应.
保存建议
提供的HtrA2/Omi抗体 产品为100 ug 无色溶液，其浓度为0.5 mg/ml，溶解于包含有50%甘油， 1% BSA和0.02%硫柳汞的PBS缓冲液中.请将该HtrA2/Omi抗体 产品置于-20 ℃冷冻保存，建议分装使用以避免反复冻融.
