p70 S6 kinase and p90 Rsk kinase are the two distinct 40S ribosomal protein S6 Ser/Thr kinases present in somatic animal cells. p90 Rsk kinase is maximally activated within minutes of addition of growth factors or phorbol ester to cultured cells followed by activation of p70 S6 kinase. Both enzymes are regulated by serine/threonine phosphorylation，suggesting that specific kinases may exist upstream in the signaling pathways that regulate these kinases.
应用类型
Western blotting （1 ug/ml）， immunoprecipitation （10-20 ug/ml）， and Immunohistochemistry （10-20 ug/ml）. However， the optimal concentrations should be determined individually. The antibody recognizes p70 S6 kinase of human， mouse， and rat origins. Reactivity to other species has not been tested.
免疫原
Synthetic peptide near the C-terminus of human p70 S6 kinase
